منابع مشابه
A multicenter prospective phase II study of first-line modified FOLFIRINOX for unresectable advanced pancreatic cancer
Background FOLFIRINOX (FX) has been reported as an effective treatment for unresectable advanced pancreatic cancer. However, FX is associated with a high incidence of adverse events (AEs). A previous phase II study in Japan showed high incidences of hematological AEs, including febrile neutropenia (22.2%). A modified FX regimen (mFX) may decrease the rates of AEs and be more effective than FX b...
متن کاملThe Relationship between Modified Biophysical Profile, Standard Biophysical Profile, and Neonatal Outcomes of High-risk Pregnancies
Introduction: High-risk pregnancies can result in many complications for the fetus. In these pregnancies, different tests such as non-stress test (NST), biophysical profile (BPP), oxytocin contraction stress test (OCT), and Doppler sonography can be used to evaluate fetal health. As standard BBP requires more time and expertise, in this study, we evaluated the relationship between standard BPP,...
متن کاملActive targeting and safety profile of PEG-modified adenovirus conjugated with herceptin.
PEGylation of adenovirus (Ad) increases plasma retention and reduces immunogenicity, but decreases the accessibility of virus particles to target cells. We tested whether PEGylated Ad conjugated to Herceptin (Ad-PEG-HER) can be used to treat Her2/neu-positive cells in vitro and in vivo to demonstrate the therapeutic feasibility of this Ad formulation. Ad-PEG-HER transduced Her2/neu-overexpressi...
متن کاملClinical Safety Profile of Fluoroquinolones
Introduction Fluoroquinolones have demonstrated comparable efficacy and rates of adverse events as β-lactam and/or macrolide agents in the treatment of community-acquired and healthcare-associated infections. Fluoroquinolones currently marketed are generally considered to have good safety profiles (1–5). However, post-marketing spontaneous adverse event reports have imposed updates in the preca...
متن کاملContrast Agents: Safety Profile
Introduction Magnetic resonance contrast agents, in particular the gadolinium-based agents, are very safe and lack the nephrotoxicity (when injected intravenously) associated with iodinated contrast media. Minor adverse effects occur infrequently and include nausea, taste perversion, and hives. Whereas these agents cannot be differentiated on the basis of mild adverse effects, they do differ in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv472.105